Search Results 41 – 60 of 135
Special Considerations for Antiretroviral Therapy Use in Adolescents With HIV
… Many ARV drugs (e.g., abacavir, emtricitabine, lamivudine, tenofovir disoproxil fumarate [TDF], some protease …
Suboptimal CD4 Cell Recovery Despite Viral Suppression
… al. Switching to fixed-dose bictegravir, emtricitabine, and tenofovir alafenamide from dolutegravir plus abacavir and …
Interruption of Antiretroviral Therapy
… bridging was used for those on LA ART. If interruption of tenofovir (TFV)-containing ART is necessary in people with …
Hepatitis B Virus Infection
… routine HBV DNA testing is not recommended. However, if a tenofovir-sparing HIV regimen is being considered, some … people with HIV/HBV coinfection (median age 41 years) on tenofovir-containing antiretroviral therapy (ART), the … yearly (AIII). Special Considerations When Initiating Tenofovir-Sparing ARV Regimens In people without a history …
Hepatitis C Virus Infection
… the following: Velpatasvir can increase concentrations of tenofovir disoproxil fumarate and lead to tenofovir-related renal toxicity. It is unclear at this time whether this is also the case with tenofovir alafenamide. Nevertheless, care should be taken in …
Immune Activation and Inflammation Among People With HIV Receiving Antiretroviral Therapy
… density after initiation of antiretroviral treatment with tenofovir disoproxil fumarate/emtricitabine plus …
Optimizing Antiretroviral Therapy in the Setting of Viral Suppression
… NRTI = nucleoside reverse transcriptase inhibitor; TAF = tenofovir alafenamide; TDF = tenofovir disoproxil fumarate With currently available … switching to an ARV regimen that does not include tenofovir alafenamide (TAF) or tenofovir disoproxil fumarate …
Preventing HIV Transmission During Infant Feeding
… infant. 92 NRTIs show more variability than PIs and NNRTIs. Tenofovir concentrations from tenofovir disoproxil fumarate (TDF) are very low in breast … Plasma and breast milk pharmacokinetics of emtricitabine, tenofovir and lamivudine using dried blood and breast milk …
Herpes Simplex Virus
… . Abdool Karim SS, Abdool Karim Q, Kharsany AB, et al. Tenofovir gel for the prevention of herpes simplex virus …
Overview
… caused by atazanavir, renal tubulopathy caused by tenofovir disoproxil fumarate) usually can be managed by … . Hill A, Hughes SL, Gotham D, Pozniak AL. Tenofovir alafenamide versus tenofovir disoproxil fumarate: is there a true difference in …
Central Nervous System Toxicity
… al. Fixed-dose combination bictegravir, emtricitabine, and tenofovir alafenamide in adolescents and children with HIV: … tolerability of bictegravir combined with emtricitabine/tenofovir alafenamide in clinical practice. Antivir Ther . … co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir DF versus continuation of non-nucleoside reverse …
Dyslipidemia
… in people receiving integrase strand-transfer inhibitors, tenofovir alafenamide, or both compared with other … N, Margusino-Framinan L, et al. Treatment with tenofovir alafenamide fumarate worsens the lipid profile of HIV-infected patients versus treatment with tenofovir disoproxil fumarate, each coformulated with …
Special Populations: HIV-2 Infection
… controlled trial comparing raltegravir (RAL) plus tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) to … D, Gallien S, et al. First-line raltegravir/emtricitabine/tenofovir combination in human immunodeficiency virus type 2 … regimen of elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate for the initial treatment of …
Cardiovascular Complications in People With HIV
… of a first MACE with ART regimens, including ABC versus tenofovir-containing regimens, 32 and an increased MACE … (HDL), and triglycerides have been observed with tenofovir alafenamide (TAF), efavirenz (EFV), all boosted … who received TAF when compared with those who received tenofovir disoproxil fumarate (TDF) in multiple randomized …
Special Populations: HIV and the Older Person
… to the marked fracture risk. ART regimens that contain tenofovir disoproxil fumarate (TDF), 27 boosted protease … (INSTIs). 28-31 Abacavir (ABC), NRTI-sparing regimens, and tenofovir alafenamide (TAF) may be considered as … density after initiation of antiretroviral treatment with tenofovir disoproxil fumarate/emtricitabine plus …
Weight Gain in People With Treated HIV
… reverse transcriptase inhibitor (NNRTI)–based and tenofovir disoproxil fumarate (TDF)–based regimens. 6-9 … and the nucleotide reverse transcriptase inhibitor (NRTI) tenofovir alafenamide (TAF), 11,13 especially when compared … . Lake JE, Trevillyan J. Impact of Integrase inhibitors and tenofovir alafenamide on weight gain in people with HIV. …
Lactic Acidosis
… acidosis after concomitant treatment with metformin and tenofovir in a patient with HIV infection. J Ren Care . … M, Matsumoto M, Sawamura M. Severe lactic acidosis during tenofovir disoproxil fumarate and cobicistat combination for … Whitsett M, Papadopoulos Z, et al. Successful treatment of tenofovir alafenamide-induced lactic acidosis: a case …
Lipodystrophies and Weight Gain
… Infections Cohort Collaboration Study G. Weight gain on tenofovir alafenamide fumarate-based therapy compared to tenofovir disoproxil fumarate- and abacavir-based therapy in … Townsend CL, Milanzi E, et al. Effectiveness and safety of tenofovir alafenamide in children and adolescents living …
Nephrotoxic Effects
… . Campbell L, Barbini B, Cromarty B, et al. Safety of tenofovir alafenamide in people with HIV who experienced proximal renal tubulopathy on tenofovir. AIDS. 2024;38(9):1442-1445. Available at: … . Gupta SK, Post FA, Arribas JR, et al. Renal safety of tenofovir alafenamide vs. tenofovir disoproxil fumarate: a …
Osteopenia and Osteoporosis
… S, et al. Efficacy, safety and pharmacokinetics of tenofovir disoproxil fumarate in virologic-suppressed … B, Wang S, Cheung AM, Mishra S, Tan DH. The effect of tenofovir disoproxil fumarate on bone mineral density: a … X, et al. Vitamin D and calcium supplementation reverses tenofovir-caused bone mineral density loss in people taking …