Drug information

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Brand Name
Trogarzo
Other Names
IBA, Ibalizumab
Drug Class
Post-attachment Inhibitor
Drug Image(s): (Click to enlarge)
What are the most important things to know about ibalizumab-uiyk? What are the most important things to know about ibalizumab-uiyk?

What are the most important things to know about ibalizumab-uiyk?

Ibalizumab-uiyk can cause serious side effects, including allergic reactions.

Contact your health care provider or get medical help right away if you develop any of the following symptoms of an allergic reaction:

  • Trouble breathing
  • Swelling in your throat
  • Wheezing
  • Chest pain or tightness
  • Cough
  • Hot flush
  • Nausea or vomiting

While receiving ibalizumab-uiyk, it is important to keep all of your appointments with your health care provider.

What is ibalizumab-uiyk?What is ibalizumab-uiyk?

What is ibalizumab-uiyk?

Ibalizumab-uiyk (brand name: Trogarzo) is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults for whom other HIV medicines have not worked and who meet certain requirements, as determined by a health care provider.

Ibalizumab-uiyk is always used in combination with other HIV medicines.

For more information on the use of ibalizumab-uiyk in people with HIV, please refer to the Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV.

HIV medicines cannot cure HIV/AIDS, but taking HIV medicines every day helps people with HIV live longer, healthier lives. HIV medicines also reduce the risk of HIV transmission. If you are taking HIV medicines, do not cut down on, skip, or stop taking them unless your health care provider tells you to.

What should I tell my health care provider before taking ibalizumab-uiyk?What should I tell my health care provider before taking ibalizumab-uiyk?

What should I tell my health care provider before receiving ibalizumab-uiyk?

Before you receive ibalizumab-uiyk, tell your health care provider:

  • If you are allergic to ibalizumab-uiyk or any other medicines.
  • If you have any medical conditions.
  • If you are pregnant or plan to become pregnant. Talk to your health care provider about the risks and benefits of taking ibalizumab-uiyk during pregnancy. For more information on the use of ibalizumab-uiyk during pregnancy, please refer to the Recommendations for the Use of Antiretroviral Drugs During Pregnancy and Interventions to Reduce Perinatal HIV Transmission in the United States.
  • If you are breastfeeding or plan to breastfeed. For women with HIV in the United States, the Guideline does not recommend breastfeeding. Before your baby is born, or if you are already breastfeeding, talk to your health care provider to discuss alternative options for feeding your baby.
  • If you are using hormone-based birth control (such as pills, implants, or vaginal rings). For more information about using birth control and HIV medicines at the same time, view the HIVinfo HIV and Birth Control infographic.
  • About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
How will I receive ibalizumab-uiyk?How will I receive ibalizumab-uiyk?

How will I receive ibalizumab-uiyk?

Your health care provider will administer ibalizumab-uiyk either as an intravenous (IV) infusion given into your vein over 15 to 30 minutes or as an IV push given into your vein over 30 seconds. Your health care provider will monitor you while you are receiving ibalizumab-uiyk and for a period of time after you have received ibalizumab-uiyk.

It is important that you receive ibalizumab-uiyk as instructed by your health care provider. Do not change the schedule of your ibalizumab-uiyk IV infusion or IV push without talking to your health care provider first. Tell your healthcare provider right away if you stop receiving ibalizumab-uiyk or stop taking any other HIV medicines.

Always use ibalizumab-uiyk in combination with other HIV medicines.

For more information about how you will receive ibalizumab-uiyk, see the FDA drug label.

What should I do if I miss a dose?What should I do if I miss a dose?

What should I do if I miss a dose?

If you miss an appointment for your ibalizumab-uiyk IV infusion or IV push, contact your health care provider as soon as possible. Your health care provider will help you resume treatment.

What side effects can ibalizumab-uiyk cause?What side effects can ibalizumab-uiyk cause?

What side effects can ibalizumab-uiyk cause?

Ibalizumab-uiyk may cause side effects. Some side effects of ibalizumab-uiyk can be serious as noted above. Many side effects from HIV medicines, such as nausea or occasional dizziness, are manageable. See the HIVinfo fact sheet on HIV Medicines and Side Effects for more information.

Other possible side effects of ibalizumab-uiyk include:

  • Changes in your immune system (called immune reconstitution inflammatory syndrome or IRIS). IRIS is a condition that sometimes occurs when the immune system begins to recover after treatment with an HIV medicine. As the immune system gets stronger, it may have an increased response to a previously hidden infection.
  • Diarrhea or rash.

Tell your health care provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of ibalizumab-uiyk. To learn more about possible side effects of ibalizumab-uiyk, read the drug label or package insert or talk to your health care provider or pharmacist.

You can report side effects to FDA at 1-800-FDA-1088 (1-800-332-1088) or online.

Where can I find more information about ibalizumab-uiyk?Where can I find more information about ibalizumab-uiyk?

Where can I find more information about ibalizumab-uiyk?

More information about ibalizumab-uiyk is available:

Manufacturer Information

Theratechnologies Inc.
Main number: 514-336-7800
Patient assistance: 833-238-4372

Last Reviewed: October 9, 2022