Drug information

Audio
Pronounce:
Brand Name:
Trogarzo
Other Names:
Hu5A8, IBA, Ibalizumab, TMB-355, TNX-355
Drug Class:
Post-attachment Inhibitor
Drug Image(s): (Click to enlarge)
What are the most important things to know about ibalizumab-uiyk? What are the most important things to know about ibalizumab-uiyk?

What are the most important things to know about ibalizumab-uiyk?

Ibalizumab-uiyk can cause serious side effects, including changes in your immune system, called immune reconstitution inflammatory syndrome or IRIS. IRIS is a condition that sometimes occurs when the immune system begins to recover after treatment with an HIV medicine. As the immune system gets stronger, it may have an increased response to a previously hidden infection.

Contact your health care provider right away if you start having new symptoms after receiving ibalizumab-uiyk as these could be signs of IRIS.

While taking ibalizumab-uiyk, it is important to keep all of your appointments with your health care provider.

What is ibalizumab-uiyk?What is ibalizumab-uiyk?

What is ibalizumab-uiyk?

Ibalizumab-uiyk is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults for whom other HIV medicines have not worked and who meet certain requirements, as determined by a health care provider.

Ibalizumab-uiyk is used in combination with other HIV medicines.

HIV medicines can’t cure HIV/AIDS, but taking HIV medicines every day helps people with HIV live longer, healthier lives. HIV medicines also reduce the risk of HIV transmission. If you are taking HIV medicines, don’t cut down on, skip, or stop taking them unless your health care provider tells you to.

What should I tell my health care provider before taking ibalizumab-uiyk?What should I tell my health care provider before taking ibalizumab-uiyk?

What should I tell my health care provider before taking ibalizumab-uiyk?

Before taking ibalizumab-uiyk, tell your health care provider:

  • If you are allergic to ibalizumab-uiyk or any other medicines.
  • If you have any other medical conditions.
  • If you are pregnant or plan to become pregnant. Talk to your health care provider about the risks and benefits of taking ibalizumab-uiyk during pregnancy.
  • If you are breastfeeding or plan to breastfeed. Do not breastfeed if you have HIV or are taking ibalizumab-uiyk.
  • If you are using hormone-based birth control (such as pills, implants, or vaginal rings). For more information about using birth control and HIV medicines at the same time, view the HIVinfo HIV and Birth Control infographic.
  • About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Ibalizumab-uiyk may affect the way other medicines or products work, and other medicines or products may affect how ibalizumab-uiyk works. Taking ibalizumab-uiyk together with certain medicines or products may cause serious side effects.
How will I receive ibalizumab-uiyk?How will I receive ibalizumab-uiyk?

How will I receive ibalizumab-uiyk?

Your health care provider will administer ibalizumab-uiyk as an infusion given into your vein over 15 to 30 minutes. Your health care provider will monitor you during the infusion and for a period of time after your infusion.

You will receive ibalizumab-uiyk every 2 weeks. It is important that you receive ibalizumab-uiyk every 2 weeks as instructed by your health care provider.

Do not change the schedule of your ibalizumab-uiyk infusions without talking to your health care provider first. Tell your healthcare provider right away if you stop receiving ibalizumab-uiyk infusions or stop taking any other HIV medicines.

Ibalizumab-uiyk infusions are used in combination with other HIV medicines.

For more information on how to take ibalizumab-uiyk, see the FDA drug label.

What should I do if I miss a dose?What should I do if I miss a dose?

What should I do if I miss a dose?

If you miss an appointment for your ibalizumab-uiyk infusion, contact your health care provider as soon as possible. Your health care provider will help you resume treatment.

What side effects can ibalizumab-uiyk cause?What side effects can ibalizumab-uiyk cause?

What side effects can ibalizumab-uiyk cause?

Ibalizumab-uiyk may cause side effects. Many side effects from HIV medicines, such as nausea or occasional dizziness, are manageable. See the HIVinfo fact sheet on HIV Medicines and Side Effects for more information.

Some side effects of ibalizumab-uiyk can be serious. A serious side effect of ibalizumab-uiyk is changes in your immune system (called immune reconstitution inflammatory syndrome or IRIS). (See section above: What are the most important things to know about ibalizumab-uiyk?)

Other possible side effects of ibalizumab-uiyk include diarrhea or rash.

Tell your health care provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of ibalizumab-uiyk. To learn more about possible side effects of ibalizumab-uiyk, read the drug label or package insert or talk to your health care provider or pharmacist.

You can report side effects to FDA at 1-800-FDA-1088 (1-800-332-1088) or online.

Where can I find more information about ibalizumab-uiyk?Where can I find more information about ibalizumab-uiyk?

Where can I find more information about ibalizumab-uiyk?

More information about ibalizumab-uiyk is available:

Manufacturer Information

TaiMed Biologics USA Corp.
Main number: 949-769-6543
Patient assistance: 833-238-4372

The above Patient Version drug summary is based on the following FDA label(s): Injection.

Last Reviewed: February 17, 2020