Drug information
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What is moxifloxacin hydrochloride?
Moxifloxacin hydrochloride is an antibacterial prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of certain bacterial infections, such as community-acquired pneumonia, acute worsening of chronic bronchitis, acute sinus infections, plague, and skin and abdominal infections.
Community-acquired pneumonia, a bacterial respiratory infection, can be an opportunistic infection (OI) of HIV. An OI is an infection that occurs more frequently or is more severe in people with weakened immune systems —such as people with HIV—than in people with healthy immune systems. To learn more about OIs, read the HIVinfo What is an Opportunistic Infection? fact sheet.
How is moxifloxacin hydrochloride used in people with HIV?
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV include recommendations on the uses of moxifloxacin hydrochloride to:
Treat:
- Community-acquired pneumonia
- Disseminated Mycobacterium avium complex (MAC) infection
- Active tuberculosis (TB) disease
- Certain bacterial enteric infections, such as salmonellosis (also known as Salmonella infection), shigellosis, and campylobacteriosis
Prevent:
- Disseminated MAC infection from recurring
What should I tell my health care provider before using moxifloxacin hydrochloride?
Before using moxifloxacin hydrochloride, tell your health care provider:
- If you are allergic to moxifloxacin hydrochloride or any other medicines.
- About any medical conditions you have or have had, including:
- Myasthenia gravis (a disease that causes muscle weakness)
- Tendon, bone, or joint problems, including rheumatoid arthritis
- liver or kidney problems
- Central nervous system problems, including mental health problems, epilepsy, or seizures
- Nerve problems, such as peripheral neuropathy
- Diabetes or problems with low blood sugar (hypoglycemia)
- Heart problems
- Low potassium or low magnesium
- Salt-restricted diet
- About anything that could affect your ability to take medicines, such as difficulty swallowing pills, difficulty remembering to take pills, or any health conditions that may prevent your use of intravenous medicines.
- If you are pregnant or plan to become pregnant. Talk to your health care provider about the risks and benefits of using moxifloxacin hydrochloride during pregnancy. The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV may include other recommendations on the use of moxifloxacin hydrochloride during pregnancy. Please refer to these guidelines for additional information.
- If you are breast/chestfeeding or plan to breast/chestfeed. For people with HIV in the United States, the Guideline recommends speaking with your health care provider to discuss options for feeding your baby. People with suppressed viral load have a less than 1% chance of transmitting HIV to their baby via their own milk.
- About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Moxifloxacin hydrochloride may affect the way other medicines or products work, and other medicines or products may affect how moxifloxacin hydrochloride works. Ask your health care provider if there are interactions between moxifloxacin hydrochloride and the other medicines you take.
Ask your health care provider about possible side effects from moxifloxacin hydrochloride. Your health care provider will tell you what to do if you have side effects.
How should I use moxifloxacin hydrochloride?
Use moxifloxacin hydrochloride according to your health care provider’s instructions. Your health care provider will tell you how much moxifloxacin hydrochloride to use and when to use it. Before you start moxifloxacin hydrochloride and each time you get a refill, read any printed information that comes with your medicine.
How should moxifloxacin hydrochloride be stored?
- Store moxifloxacin hydrochloride tablets at room temperature between 68°F to 77°F (20°C to 25°C) and away from moisture (humidity).
- Store moxifloxacin hydrochloride injection solution at room temperature between 68°F to 77°F (20°C to 25°C). Keep the moxifloxacin hydrochloride injection bag in the outer bag and away from light until ready to use. Do not refrigerate.
- Do not use moxifloxacin hydrochloride if the original seal over the medicine container is broken or missing.
- Throw away moxifloxacin hydrochloride that is no longer needed or expired (out of date). Follow FDA guidelines on how to safely dispose of unused medicine.
- Keep moxifloxacin hydrochloride and all medicines out of reach of children.
Where can I find more information about moxifloxacin hydrochloride?
- Recommendations on the HIV-related uses of moxifloxacin hydrochloride, from the Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV.
- The Patient Version drug summary is based on the following FDA label(s): Injection (solution); Tablet (film coated). The Medication Guide includes information for people taking moxifloxacin hydrochloride.
- The American Formulary Service (AHFS) Patient Medication Information for moxifloxacin hydrochloride available from MedlinePlus.
- Moxifloxacin hydrochloride-related research studies, from ClinicalTrials.gov. (The ClinicalTrials.gov search can be modified so that you can get results that better match your interests.)
Last Reviewed: July 18, 2023