Integrase Strand Transfer Inhibitor (INSTI)

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Synonym(s)
Integrase Inhibitor

Antiretroviral (ARV) HIV drug class. Integrase strand transfer inhibitors (INSTIs) block integrase (an HIV enzyme). HIV uses integrase to insert (integrate) its viral DNA into the DNA of the host CD4 cell. Blocking integrase prevents HIV from replicating.

Related Term(s)
Drug Class
Integrase
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Integrase Strand Transfer Inhibitor (INSTI) is an HIV drug class which block integrase (an HIV enzyme).
Integration is the step in the HIV life cycle where HIV uses integrase to insert its viral DNA into the DNA of the host cell.

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