HIV/AIDS Glossary

An infection caused by herpes simplex virus 2 (HSV-2) and usually associated with lesions in the genital or anal area. HSV-2 is very contagious and is transmitted by direct contact, including sexual contact, with someone who has the virus (even if lesions are not visible). Treatment cannot completely clear HSV-2 from the body, but antiviral therapy can shorten and prevent outbreaks and reduce the likelihood of transmission. People who have both HIV and HSV-2 are more likely to transmit HIV to a partner who does not have HIV during sexual contact.