Herpes Simplex Virus 1 (HSV-1) Infection

An infection caused by herpes simplex virus 1 (HSV-1) and usually associated with lesions on the lips, mouth, and face. HSV-1 is very contagious and is transmitted by direct contact, including sexual contact, with someone who has the virus (even if lesions are not visible). Treatment cannot completely clear HSV-1 from the body, but antiviral therapy can shorten and prevent outbreaks and reduce the risk of transmission. People who have both HIV and HSV-1 have a higher risk of transmitting HIV to a partner who does not have HIV during sexual contact.


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