Drug information

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Antifungal (Azole)
What is terconazole?What is terconazole?

What is terconazole?

Terconazole is an antifungal prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of vulvovaginal candidiasis, which is an infection of the female vulva and vagina and is a type of mucocutaneous candidiasis.

Mucocutaneous candidiasis (also called mucosal candidiasis) can be an opportunistic infection (OI) of HIV. An OI is an infection that occurs more frequently or is more severe in people with weakened immune systems—such as people with HIV—than in people with healthy immune systems. To learn more about OIs, read the HIVinfo What is an Opportunistic Infection? fact sheet.

How is terconazole used in people with HIV?How is terconazole used in people with HIV?

How is terconazole used in people with HIV?

The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV include recommendations on the use of terconazole to treat uncomplicated vulvovaginal candidiasis.

The recommended uses may not always be consistent with FDA-approved uses of terconazole. See the Guidelines for complete information on recommended uses of terconazole in adults and adolescents with HIV. Terconazole may also be recommended for use in other rare circumstances not listed above.

What should I tell my health care provider before taking terconazole?What should I tell my health care provider before taking terconazole?

What should I tell my health care provider before using terconazole?

Before using terconazole, tell your health care provider:

  • If you are allergic to terconazole or any other medicines.
  • About any medical conditions you have or have had, for example, diabetes or yeast infections.
  • About anything that could affect your ability to take medicines, such as difficulty with remembering when to take medicines.
  • If you are pregnant or plan to become pregnant. Terconazole should not be used in the first trimester of pregnancy unless it is essential for your health. Terconazole may be used during the second and third trimester if the potential benefit outweighs the possible risks to the fetus. Talk to your health care provider about the risks and benefits of taking terconazole during pregnancy. The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV may include other recommendations on the use of terconazole during pregnancy. Please refer to these guidelines for additional information.
  • If you are breastfeeding or plan to breastfeed. For women with HIV in the United States, the Guideline does not recommend breastfeeding. Before your baby is born, or if you are already breastfeeding, talk to your health care provider to discuss alternative options for feeding your baby.
  • About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Terconazole may affect the way other medicines or products work, and other medicines or products may affect how terconazole works. Ask your health care provider if there are interactions between terconazole and the other medicines you take.

Ask your health care provider about possible side effects from terconazole. Your health care provider will tell you what to do if you have side effects.

How should I take terconazole?How should I take terconazole?

How should I use terconazole?

Use terconazole according to your health care provider’s instructions. Your health care provider will tell you how much terconazole to use and when to use it. Before you start terconazole and each time you get a refill, read any printed information that comes with your medicine.

How should terconazole be stored?How should terconazole be stored?

How should terconazole be stored?

  • Store terconazole vaginal cream (0.8%) at room temperature, 68°F to 77°F (20°C to 25°C).
  • Store terconazole vaginal suppositories at room temperature, 68°F to 77°F (20°C to 25°C).
  • Do not use terconazole if the original seal over the container opening is broken or missing.
  • Throw away terconazole that is no longer needed or expired (out of date). Follow FDA guidelines on how to safely dispose of unused medicine.
  • Keep terconazole and all medicines out of reach of children.
Where can I find more information about terconazole?Where can I find more information about terconazole?

Where can I find more information about terconazole?

Last Reviewed: January 11, 2021