What is levofloxacin?
Levofloxacin is an antibacterial prescription medicine approved by the U.S.(FDA) for the treatment of certain bacterial infections, such as community-acquired , acute worsening of chronic bronchitis, anthrax, urinary tract infections, acute sinus infections, and others.
Community-acquired pneumonia, a bacterial respiratory infection, can be an What is an Opportunistic Infection? fact sheet.(OI) of HIV. An OI is an that occurs more frequently or is more severe in people with weakened immune systems—such as people with HIV—than in people with healthy immune systems. To learn more about OIs, read the HIVinfo
How is levofloxacin used in people with HIV?
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV include recommendations on the uses of levofloxacin in people with HIV to:Treat:
- Community-acquired pneumonia
- Active (TB) disease
- Certain bacterial infections, such as salmonellosis (also known as infection), , and
- Disseminated MAC infection from recurring
The recommended uses may not always be consistent with FDA-approved uses of levofloxacin. See the guidelines for complete information on recommended uses of levofloxacin in adults and adolescents with HIV. Levofloxacin may have other recommended uses not listed above.
What should I tell my health care provider before using levofloxacin?
Before using levofloxacin, tell your health care provider:
- If you are allergic to levofloxacin or any other medicines.
- About any medical conditions you have or have had, including:
- Myasthenia gravis (a disease that causes muscle weakness)
- Tendon, bone, or joint problems, including rheumatoid arthritis
- or problems with low blood sugar (hypoglycemia)
- Heart problems
- Low potassium or low magnesium
- About anything that could affect your ability to take medicines, such as difficulty swallowing pills, difficulty remembering to take pills, or any health conditions that may prevent your use of medicines.
- If you are pregnant or plan to become pregnant. Levofloxacin should be used during pregnancy only if the potential benefit justifies the potential risk to the Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV may include other recommendations on the use of levofloxacin during pregnancy. Please refer to these guidelines for additional information. . Talk to your health care provider about the risks and benefits of using levofloxacin during pregnancy. The
- If you are breastfeeding or plan to breastfeed. For women with HIV in the United States, the Guideline does not recommend breastfeeding. Before your baby is born, or if you are already breastfeeding, talk to your health care provider to discuss alternative options for feeding your baby.
- About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Levofloxacin may affect the way other medicines or products work, and other medicines or products may affect how levofloxacin works. Ask your health care provider if there are interactions between levofloxacin and the other medicines you take.
Ask your health care provider about possible side effects from levofloxacin. Your health care provider will tell you what to do if you have side effects.
How should I use levofloxacin?
Use levofloxacin according to your health care provider’s instructions. Your health care provider will tell you how much levofloxacin to use and when to use it. Before you start levofloxacin and each time you get a refill, read any printed information that comes with your medicine.
How should levofloxacin be stored?
- Store levofloxacin tablets and injection solution at room temperature, 68°F to 77°F (20°C to 25°C).
- Store levofloxacin oral solution at 59°F to 86°F (15°C to 30°C).
- Keep levofloxacin in the container that it came in and keep the container tightly closed.
- Do not use levofloxacin if the original seal over the container opening is broken or missing.
- Throw away levofloxacin that is no longer needed or expired (out of date). Follow FDA guidelines on how to safely dispose of unused medicine.
- Keep levofloxacin and all medicines out of reach of children.
Where can I find more information about levofloxacin?
More information about levofloxacin is available:
- Recommendations on the HIV-related uses of levofloxacin, from the Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV, prepared by the , the , and the HIV Medicine Association of the Diseases Society of America
- Levofloxacin-related research studies, from
Last Reviewed: March 12, 2021