What is doxycycline?
Doxycycline is an antibacterial prescription medicine approved by the U.S.(FDA) for the treatment of certain . In addition, doxycycline is FDA-approved for the prevention of due to Plasmodium falciparum.
Many of the infections for which doxycycline is FDA-approved can be What is an Opportunistic Infection? fact sheet.(OIs) of HIV. An OI is an infection that occurs more frequently or is more severe in people with weakened —such as people with HIV—than in people with healthy immune systems. To learn more about OIs, read the HIVinfo
How is doxycycline used in people with HIV?
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV and the Guidelines for the Prevention and Treatment of Opportunistic Infections in Children with and Exposed to HIV include recommendations on the uses of doxycycline in people with HIV to:
- Certain Bartonella infections (also called )
- Certain Bartonella infections (also called bartonellosis)
The recommended uses may not always be consistent with FDA-approved uses of doxycycline. See the Adult and Pediatric Opportunistic Infection Guidelines for complete information on recommended uses of doxycycline in adults and children with HIV. Doxycycline may have other recommended uses not listed above.
What should I tell my health care provider before taking doxycycline?Before taking doxycycline, tell your health care provider:
- If you are allergic to doxycycline or any other medicines.
- About any medical conditions you have or have had.
- About anything that could affect your ability to take medicines, such as difficulty swallowing pills, difficulty remembering to take pills, or any health conditions that may prevent you from receiving medicine by injection or infusion.
- If you are pregnant or plan to become pregnant. Talk to your health care provider about the risks and benefits of taking doxycycline during pregnancy. The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV may include other recommendations on the use of doxycycline during pregnancy. Please refer to these guidelines for additional information.
- If you are breast/chestfeeding or plan to breast/chestfeed. For people with HIV in the United States, the Guideline recommends speaking with your health care provider to discuss options for feeding your baby. People with suppressed viral load have a less than 1% chance of transmitting HIV to their baby via their own milk.
- About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Doxycycline may affect the way other medicines or products work, and other medicines or products may affect how doxycycline works. Ask your health care provider if there are interactions between doxycycline and the other medicines you take.
Take doxycycline according to your health care provider’s instructions. Your health care provider will tell you how much doxycycline to take and when to take it. Before you start doxycycline and each time you get a refill, read any printed information that comes with your medicine.
How should doxycycline be stored?
- Store doxycycline capsules and oral suspension below 86°F (30°C).
- Store doxycycline tablets at 77°F (25°C); excursions permitted to 59°F to 86°F (15°C to 30°C).
- Store doxycycline sterile powder for injection between 68°F and 77°F (20°C and 25°C) and protect from direct sunlight during storage and infusion.
- Do not use doxycycline if the original seal over the container opening is broken or missing.
- Throw away doxycycline that is no longer needed or expired (out of date). Follow FDA guidelines on how to safely dispose of unused medicine.
- Keep doxycycline and all medicines out of reach of children.
Where can I find more information about doxycycline?
- Recommendations on the HIV-related uses of doxycycline, from the Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV and the Guidelines for the Prevention and Treatment of Opportunistic Infections in Children with and Exposed to HIV.
- This Patient Version drug summary is based on the following FDA label(s):
- Injection (powder, lyophilized, for solution). Toward the end of the label is patient information for people taking doxycycline.
- Powder (for suspension), syrup, capsule. Toward the end of the label is patient information for people taking doxycycline
- Tablet (delayed release). The Patient Counseling Information section of the label includes information for people taking doxycycline.
- The American Hospital Formulary Service (AHFS) Patient Medication Information for doxycycline available from MedlinePlus:
- Doxycycline-related research studies, from ClinicalTrials.gov. (The ClinicalTrials.gov search can be modified so that you can get results that better match your interests. To learn more about the ClinicalTrials.gov search features, please see How to Search.)
Last Reviewed: January 3, 2023