What are the most important things to know about Juluca?
Juluca can cause serious, life-threatening side effects. These include severe skin rash and allergic reactions,problems, .
Contact your health care provider right away if you develop a rash while taking Juluca. Stop taking Juluca and get medical help right away if you develop a rash with any of the following signs or symptoms:
- General ill feeling
- Extreme tiredness
- Muscle or joint aches
- Blistering or peeling skin
- Blisters or sores in your mouth
- Redness or swelling of the eyes (
- Swelling of your face, lips, mouth, tongue, or throat
- Trouble breathing or swallowing
Some people taking Juluca may develop liver problems. People with a history of(HBV) or (HCV) may have an increased risk of developing new or worsening liver problems while taking Juluca. Liver function tests may be done before and during treatment with Juluca.
Contact your health care provider right away if you develop any of the following symptoms that could be signs of liver problems:
- Yellowing of your skin or the whites of your eyes ( )
- Dark-colored urine
- Light-colored bowel movements
- Loss of appetite for several days or longer
- Nausea or vomiting
- Pain, aching, or tenderness on the right side of your stomach area/abdominal area
Contact your health care provider right away or get medical help if you have any of the following symptoms that could be signs of depression or mood changes:
- Feeling sad or hopeless
- Feeling anxious or restless
- Harming yourself or having thoughts about harming yourself (including suicidal thoughts)
Taking Juluca with certain other medicines may result in serious, life-threatening side effects. Tell your health care provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
While taking Juluca, it is important to keep all of your appointments with your health care provider.
What is Juluca?
Juluca is a prescription medicine approved by the U.S.(FDA) for the treatment of HIV in adults who meet specific requirements, as determined by a health care provider.
Juluca is a complete HIVand should not be used with other HIV medicines.
For more information on the use of Juluca in people with HIV, please refer to the Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents with HIV.
What should I tell my health care provider before taking Juluca?
Before taking Juluca, tell your health care provider:
- If you are allergic to any of the HIV medicines in Juluca (dolutegravir or rilpivirine) or any other medicines.
- If you have or have ever had problems, including
- If you have ever had a mental health problem.
- If you have any other medical conditions.
- If you are pregnant or plan to become pregnant. Talk to your health care provider about the risks and benefits of taking Juluca during pregnancy. For more information on the use of Juluca during pregnancy, please refer to the Recommendations for the Use of Antiretroviral Drugs During Pregnancy and Interventions to Reduce Perinatal HIV Transmission in the United States.
- If you are breast/chestfeeding or plan to breast/chestfeed. For people with HIV in the United States, the Guideline recommends speaking with your health care provider to discuss options for feeding your baby. People with suppressed viral load have a less than 1% chance of transmitting HIV to their baby via their own milk.
- If you are using HIV and Birth Control infographic. -based birth control (such as pills, , or vaginal rings). For more information about using birth control and HIV medicines at the same time, view the HIVinfo
- About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products (particularly St. John’s wort) you are taking or plan to take. Juluca may affect the way other medicines or products work, and other medicines or products may affect how Juluca works. Taking Juluca together with certain medicines or products may cause serious, life-threatening side effects.
How should I take Juluca?
Juluca comes in tablet form. Each tablet contains:
Take Juluca according to your health care provider’s instructions. Do not miss aof Juluca, and do not change your dose or stop taking Juluca without first talking with your health care provider.
Always take Juluca by mouth and with a meal. (Adrink is not a substitute for a meal.)
If you are taking H2 blockers or(medicines for reducing stomach acid); laxatives; other products containing aluminum, calcium carbonate, magnesium; or buffered medicines (such as buffered aspirin), carefully follow instructions on how to take them with Juluca.
Proton pump inhibitors (medicines for reducing stomach acid) should NOT be taken with Juluca.
If you have taken too much Juluca, contact your health care provider or local poison control center (1-800-222-1222) right away, or go to the nearest hospital emergency room.
For more information on how to take Juluca, see the FDA drug label.
What should I do if I forget a dose?
If you miss aof Juluca, take the missed dose as soon as you remember it. (Take the missed dose with a meal.) But if it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.
What side effects can Juluca cause?
Juluca may cause side effects. Some side effects of Juluca can be serious as noted above. Many side effects from HIV medicines, such as nausea or occasional dizziness, are manageable. See the HIVinfo fact sheet on HIV Medicines and Side Effects for more information.
Other possible side effects of Juluca include diarrhea and headache.
Tell your health care provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of Juluca. To learn more about possible side effects of Juluca, read the drug label or or talk to your health care provider or pharmacist.
You can report side effects to FDA at 1-800-FDA-1088 (1-800-332-1088) or online.
How should Juluca be stored?
- Store Juluca at room temperature, 68°F to 77°F (20°C to 25°C).
- Keep Juluca in the container that it came in. Keep the container tightly closed and away from moisture. If the container has a small packet of drying agent (called a ), do not remove it. The desiccant protects the medicine from moisture.
- Do not use Juluca if the original seal over the container opening is broken or missing.
- Throw away Juluca that is no longer needed or expired (out of date). Follow FDA guidelines on how to safely dispose of unused medicine.
- Keep Juluca and all medicines out of reach of children.
Where can I find more information about Juluca?
- For more information on the use of Juluca in people with HIV, please refer to the Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents with HIV.
- This Patient Version drug summary is based on the following FDA label(s): Tablet, film-coated. The Patient Package Insert includes information for people taking Juluca.
- Juluca-related research studies, from . (The ClinicalTrials.gov search can be modified so that you can get results that better match your interests. To learn more about the ClinicalTrials.gov search features, please see How to Search.)
- A list of FDA-approved HIV medicines, from HIVinfo.
Main number: 877-844-8872
Patient assistance (ViiV Connect): 844-588-3288
Last Reviewed: December 27, 2022