Appendix A, Table 1. Antiretrovirals Available in Fixed-Dose Combination Tablets or as a Co-packaged Formulation, by Drug Class

Body
Appendix A, Table 1. Antiretrovirals Available in Fixed-Dose Combination Tablets or as a Co-packaged Formulation, by Drug Class
Brand Name NRTIs NNRTIs INSTIs PIs PK Enhancers
ABC 3TC ZDV FTC TDF TAFa DOR EFV RPVb BICa CABb DTG EVGa ATV DRV LPVc COBI RTV
NRTI
Cimduo   X     X                          
Combivir   X X                              
Descovy       X   X                        
Epzicom X X                                
Temixys   X     X                          
Truvada       X X                          
NRTI/NNRTI
Atripla       X X     X                    
Complera       X X       X                  
Delstrigo   X     X   X                      
Odefsey       X   X     X                  
Symfi or Symfi Lo   X     X     X                    
NRTI/INSTI
Biktarvy       X   X       X                
Dovato   X                   X            
Triumeq X X                   X            
NNRTI/INSTI
Juluca                 X     X            
Cabenuva                 X   X              
NRTI/INSTI/COBI
Genvoya       X   X             X       X  
Stribild       X X               X       X  
NRTI/PI/COBI
Symtuza       X   X                 X   X  
PI/COBI
Evotaz                           X     X  
Prezcobix                             X   X  
PI/RTV
Kaletra                               X   X
a TAF, BIC, and EVG are only available in FDC tablets. However, TAF 25 mg tablets (Vemlidy) are FDA-approved for treatment of HBV. In select circumstances, TAF might be used as one component of a combination ARV regimen, with dosing recommendations similar to those for Descovy.

b CAB and RPV for intramuscular injection are available as a co-packaged product (Cabenuva); oral formulations of CAB and RPV for initial lead in dosing must be prescribed separately, see Cabotegravir and Rilpivirine.

c LPV is only available in FDC tablets or solution.

Key to Acronyms: 3TC = lamivudine; ABC = abacavir; ARV = antiretroviral; ATV = atazanavir; BIC = bictegravir; CAB = cabotegravir; COBI = cobicistat; DOR = doravirine; DRV = darunavir; DTG = dolutegravir; EFV = efavirenz; EVG = elvitegravir; FDA = U.S. Food and Drug Administration; FDC = fixed-dose combination; FTC = emtricitabine; HBV = hepatitis B virus; INSTI = integrase strand transfer inhibitor; LPV = lopinavir; NNRTI = non-nucleoside reverse transcriptase inhibitor; NRTI = nucleoside and nucleotide reverse transcriptase inhibitor; PI = protease inhibitor; PK = pharmacokinetic; RPV = rilpivirine; RTV = ritonavir; TAF = tenofovir alafenamide; TDF = tenofovir disoproxil fumarate; ZDV = zidovudine

 

Back