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Hepatitis B Virus/HIV Coinfection
… be stopped in people with HBV/HIV (AII).  Before Initiating Tenofovir-Sparing Antiretroviral Regimens People with HIV … should have their HBV status verified before initiating a tenofovir-sparing ARV regimen. See  Optimizing … must be given if the selected ARV regimen does not contain tenofovir (AII).  TAF or TDF are preferred for HBV treatment …
Special Populations: Adolescents and Young Adults With HIV
… regimens. Bictegravir (BIC) coformulated with tenofovir alafenamide (TAF) and emtricitabine (FTC) also has … risk of side effects, such as bone and renal toxicity with tenofovir-based drugs in rapidly growing adolescents. These … peak bone mass, TAF generally should be used instead of tenofovir disoproxil fumarate, because of a greater bone …
Hepatitis C Virus
… DAA regimens. Additionally, the improved safety profile of tenofovir alafenamide (TAF) combined with safety data in the … HBV = hepatitis B virus; HCV = hepatitis C virus; TDF = tenofovir disoproxil fumarate A limited pre-treatment … also increase velpatasvir exposure, which in turn increases tenofovir plasma exposure particularly when administered as …
Special Populations: Early (Acute and Recent) HIV Infection
… ARV regimens is recommended b (AIII): Bictegravir (BIC)/tenofovir alafenamide (TAF)/emtricitabine (FTC) Dolutegravir (DTG) with (TAF or tenofovir disoproxil fumarate [TDF]) c plus (FTC or … of the INSTI genotype. c TAF and TDF are two forms of tenofovir that are approved in the United States. TAF has …
Modifying Antiretroviral Regimens in Children With Sustained Virologic Suppression on Antiretroviral Therapy
… include coformulated bictegravir, emtricitabine, and tenofovir alafenamide (BIC/FTC/TAF) (Biktarvy) or FTC/TAF … weighing ≥45 kg showed that switching to the FDC DOR/3TC/tenofovir disoproxil (TDF) resulted in maintained … no known mutations associated with resistance to DRV or tenofovir. Must be taken with food. Aged ≥12 years Weighing …
Hepatitis C Virus/HIV Coinfection
… HBV = hepatitis B virus; HCV = hepatitis C virus; TAF = tenofovir alafenamide; TDF = tenofovir disoproxil fumarate The treatment of hepatitis C … HBV (positive HBsAg) should receive ART that includes tenofovir alafenamide or tenofovir disoproxil fumarate, or …
Tuberculosis/HIV Coinfection
… or clinically suspected INSTI resistance) (AIII). Tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC) (AIII), tenofovir alafenamide (TAF)/FTC (BIII), or abacavir … DTG dosing (AII). When prescribing either 1HP or 3HP, tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC) …
Recognizing and Managing Antiretroviral Treatment Failure
… nucleos(t)ide reverse transcriptase inhibitors, (i.e., tenofovir disoproxil fumarate or tenofovir alafenamide with lamivudine (3TC) or … therapies included abacavir (ABC) and lamivudine (3TC), tenofovir disoproxil fumarate (TDF) and 3TC or TDF and …
Long-Term Follow-Up of Infants Exposed to Antiretroviral Drugs
… HIV transmission. 2,90 In addition, newer NRTIs, such as tenofovir, have not been associated with the same degree of … of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse … Stray KM, Park Y, Babusis D, et al. Tenofovir alafenamide (TAF) does not deplete mitochondrial …
Special Populations: Substance Use Disorders and HIV
… with HBV/HIV coinfection unless HBV-active drugs (i.e., tenofovir, entecavir) are included in the regimen. Because … in an urban safety-net HIV clinic reported increases in tenofovir-reactive urine tests and stimulant-negative urine …
Special Populations: Transplantation in People With HIV
… and efficacy of the new regimen before transplant (BIII). Tenofovir alafenamide (TAF) is preferred over tenofovir disoproxil fumarate (TDF) in transplant candidates … = raltegravir; RPV = rilpivirine; RTV = ritonavir; TDF = tenofovir disoproxil fumarate; TDM = therapeutic drug …
Special Populations: Women With HIV
… by HIV and some ARV drugs. 19-22 ARV regimens that contain tenofovir disoproxil fumarate (TDF), boosted protease … a 12.3­kg weight gain was recorded among women receiving tenofovir alafenamide (TAF)/emtricitabine (FTC)/DTG compared … Two small studies showed no difference in plasma levels of tenofovir and RAL between pre- and postmenopausal women. …
Overview
… Inhibitors (NRTIs) Abacavir Emtricitabine Lamivudine Tenofovir alafenamide Tenofovir disoproxil fumarate Zidovudine Non-Nucleoside …
Herpes Simplex Virus
… In clinical trials, pre-exposure prophylaxis with vaginal tenofovir gel and oral tenofovir disoproxil fumarate (TDF) or with … Karim SS, Frohlich JA, et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the …
Drug Name Abbreviations
… saquinavir SQV/r saquinavir/ritonavir T-20 enfuvirtide TAF tenofovir alafenamide TDF tenofovir disoproxil fumarate TFV tenofovir TFV-DP tenofovir diphosphate TMR temsavir TPV …
Atazanavir
… and weighing ≥40 kg if they are not concurrently taking tenofovir disoproxil fumarate (TDF) or tenofovir alafenamide (TAF), the Panel does not recommend … ATV. Nucleoside reverse transcriptase inhibitors (NRTIs): Tenofovir disoproxil fumarate (TDF) decreases ATV plasma …
Doravirine
… Tablet [Delstrigo] Doravirine 100 mg/lamivudine 300 mg/tenofovir disoproxil fumarate 300 mg When using FDC tablets, … with resistance to DOR [Delstrigo] DOR/Lamivudine (3TC)/Tenofovir Disoproxil Fumarate (TDF) Child and Adolescent … in the study used a backbone of lamivudine [3TC] plus tenofovir disoproxil fumarate [TDF]). 3 A similar effect of …
Emtricitabine
… Tablets [Generic] Efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg [Biktarvy] Bictegravir 50 mg/emtricitabine 200 mg/tenofovir alafenamide 25 mg Bictegravir 30 mg/emtricitabine 120 mg/tenofovir alafenamide 15 mg [Complera] Emtricitabine 200 …
Darunavir
… Darunavir 800 mg/cobicistat 150 mg/emtricitabine 200 mg/tenofovir alafenamide 10 mg When using FDC tablets, refer to … once daily with food [Symtuza] DRV/COBI/Emtricitabine (FTC)/Tenofovir Alafenamide (TAF) Child and Adolescent (Weighing … no known mutations associated with resistance to DRV or tenofovir. Skin rash, including Stevens-Johnson syndrome and …
Tenofovir AF
… Updated September 30, 2025 Reviewed September 30, 2025 Tenofovir Alafenamide (TAF, Vemlidy) Formulations Tablet: 25 … Tablets [Biktarvy] Bictegravir 50 mg/emtricitabine 200 mg/tenofovir alafenamide 25 mg Bictegravir 30 mg/emtricitabine 120 mg/tenofovir alafenamide 15 mg [Descovy] Emtricitabine 200 …