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What to Start: Initial Combination Antiretroviral Regimens
… transfer inhibitor; PrEP = pre-exposure prophylaxis; TAF = tenofovir alafenamide; TDF = tenofovir disoproxil fumarate; TFV = tenofovir Table 6b. Initial Antiretroviral Regimens for …
What to Start: Antiretroviral Treatment Regimens Recommended for Initial Therapy in Infants and Children With HIV
… fixed-dose combination (FDC) tablet BIC/emtricitabine (FTC)/tenofovir alafenamide (TAF). INSTI-based regimens have … that include TAF have varying weight and age requirements. Tenofovir disoproxil fumarate (TDF) plus 3TC or FTC for … (DRV/r), or lopinavir/ritonavir (LPV/r) increases plasma tenofovir (TFV) concentrations and the risk of …
Recommendations for Use of Antiretroviral Drugs During Pregnancy: Overview
… with using Preferred and Alternative ARV drugs other than tenofovir disoproxil fumarate, emtricitabine, lamivudine, … especially among women and people also receiving tenofovir alafenamide (see Dolutegravir and Tenofovir Alafenamide ). 16,17 However, it is difficult to …
What to Start: Nucleoside Reverse Transcriptase Inhibitor Options
… for HBV without adding a potent anti-HBV therapy, such as tenofovir or entecavir. Consider alternative ARV medications … reverse transcriptase inhibitor; RPV = rilpivirine; TAF = tenofovir alafenamide; TC = total cholesterol; TDF = tenofovir disoproxil fumarate Summary Ten nucleos(t)ide …
What to Start: Integrase Strand Transfer Inhibitor Regimens
… RAL = raltegravir; STR = single-tablet regimen; TAF = tenofovir alafenamide; UGT = uridine diphosphate … INSTIs BIC and DTG have high barriers to resistance, BIC/tenofovir alafenamide (TAF)/‌emtricitabine (FTC), DTG plus (TAF or tenofovir disoproxil fumarate [TDF]) plus (FTC or lamivudine …
Initial Use of Antiretroviral Therapy During Pregnancy
… (INSTIs) dolutegravir (DTG) or bictegravir (BIC) plus a tenofovir-containing dual–‍nucleoside reverse transcriptase … Infection ) (AIII). Preferred regimens include: DTG plus (tenofovir disoproxil fumarate [TDF] or tenofovir alafenamide [TAF]) plus (emtricitabine [FTC] or …
What to Start: Non-Nucleoside Reverse Transcriptase Inhibitor Regimens
… syndrome; STR = single-tablet regimen; TAF = tenofovir alafenamide; TDF = tenofovir disoproxil fumarate; TEN = toxic epidermal … trial, 734 treatment-naive participants received either DOR/tenofovir disoproxil fumarate (TDF)/lamivudine (3TC) or …
What to Start: Protease Inhibitor–Based Regimens
… applicable; PK = pharmacokinetic; RTV = ritonavir; TAF = tenofovir alafenamide Summary Ten protease inhibitors (PIs) … trial that compared the single-tablet regimen (STR) DRV/c/tenofovir alafenamide (TAF)/emtricitabine (FTC) with DRV/c plus tenofovir disoproxil fumarate (TDF)/FTC. At 48 weeks, …
Previous Experience With Antiretroviral Medications but Not Currently on Antiretroviral Therapy During Current Pregnancy
… the use of the PI darunavir boosted with ritonavir with (tenofovir alafenamide or tenofovir disoproxil fumarate)plus (emtricitabine or …
What to Start: Other Antiretroviral Regimens When Abacavir and Tenofovir Cannot Be Used or Are Not Optimal
… Antiretroviral Regimens for Initial Therapy When Abacavir, Tenofovir Alafenamide, and Tenofovir Disoproxil Fumarate Cannot Be Used or Are Not … situations where it is desirable to avoid abacavir (ABC), tenofovir alafenamide (TAF), and tenofovir disoproxil … to Start: Other Antiretroviral Regimens When Abacavir and Tenofovir Cannot Be Used or Are Not Optimal …
What to Start: Advantages and Disadvantages of Antiretroviral Components of Initial Antiretroviral Therapy
… RTV = ritonavir; STR = single-tablet regimen; TAF = tenofovir alafenamide; TDF = tenofovir disoproxil fumarate; UGT = uridine diphosphate …
Lack of Viral Suppression While on Antiretroviral Therapy in Pregnancy
… in South Africa (2021–2023), describing treatment with tenofovir/lamivudine/DTG initiated before 18 weeks of … in pregnancy drop postpartum in South African women on tenofovir-lamivudine-dolutegravir: a prospective cohort …
Table 6. What to Start: Initial Antiretroviral Regimens During Pregnancy
… = raltegravir; RPV = rilpivirine; RTV = ritonavir; TAF = tenofovir alafenamide; TDF = tenofovir disoproxil fumarate; ZDV = zidovudine; v/v = …
Teratogenicity
… = rilpivirine; RTV = ritonavir; T‑20 = enfuvirtide; TAF = tenofovir alafenamide; TDF = tenofovir disoproxil fumarate; ZDV = zidovudine For …
Hepatitis B Virus/HIV Coinfection
… administration of a HBV vaccines series (AII). Because tenofovir disoproxil fumarate (TDF), tenofovir alafenamide (TAF), lamivudine (3TC) and … coinfection during pregnancy, an ART regimen that includes tenofovir disoproxil fumarate (TDF) or tenofovir alafenamide …
HIV-2 and Pregnancy
… those recommended for treatment of HIV-1 during pregnancy: tenofovir disoproxil fumarate or tenofovir alafenamide plus emtricitabine (FTC) or lamivudine …
Early (Acute and Recent) HIV Infection
… for initial ART b (AIII): Dolutegravir (DTG) with (tenofovir alafenamide fumarate [TAF] or tenofovir disoproxil fumarate [TDF]) c plus (emtricitabine … infection, a regimen that includes dolutegravir (DTG) with tenofovir disoproxil fumarate (TDF) or tenofovir alafenamide …
Virologic Failure
… barrier plus two partially active NRTIs—particularly tenofovir alafenamide (TAF) or tenofovir disoproxil fumarate (TDF) with lamivudine (3TC) or … an HBV-active drug with a high barrier to resistance (e.g., tenofovir alafenamide [TAF], tenofovir disoproxil fumarate …
Cytomegalovirus Disease
… other potentially nephrotoxic medications, including tenofovir disoproxil fumarate. Periodic ophthalmologic …
Special Considerations for Antiretroviral Therapy Use in Adolescents With HIV
… Many ARV drugs (e.g., abacavir, emtricitabine, lamivudine, tenofovir disoproxil fumarate [TDF], some protease …